Orogen Therapeutics Advances Multiple Programs Toward IND-Enabling Studies

WOBURN, MA, March 28, 2025 – Orogen Therapeutics announced today that multiple therapeutic programs from its immuno-inflammatory pipeline have advanced toward IND-enabling studies, marking significant progress in the company's mission to develop novel oral small molecule therapeutics.
The advancement is based on compelling preclinical data demonstrating both efficacy and safety profiles for Orogen's lead compounds targeting validated cytokine pathways in immuno-inflammatory disorders.
Pipeline Progress
"Advancing multiple programs simultaneously toward clinical development demonstrates the power and efficiency of our integrated discovery platform," said Mark Pykett, CEO of Orogen Therapeutics. "We're particularly excited about the potential for these oral small molecule alternatives to current biological therapies."
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"Orogen is elevating new heights in drug discovery, integrating massive chemical libraries, target-specific screening, and AI-based computation to propel the generation of novel medicines."
Mark Pykett
CEO, Orogen Therapeutics