Driven byPurpose,Defined byInnovation.
At Orogen Therapeutics, we're pioneering transformative medicines through our innovative AI-enabled DNA-encoded library platform, focused on addressing critical unmet medical needs.
Our Unwavering Mission
Advancing Medicine,
Anchored to the Patient.
At Orogen Therapeutics, our mission is singular and profound: to expedite the development of novel medicines for patients in critical need. We believe that everyone deserves access to groundbreaking treatments, and we are relentless in our pursuit of solutions that can transform lives.
Every decision, every discovery, every endeavor is anchored firmly to the patient, reminding us why we are in biopharma – to make a tangible, positive impact on human health.
Our Guiding Principles
Patient-Centric Innovation
We place patients at the center of our work, ensuring every innovation addresses real needs.
Scientific Excellence
We maintain the highest standards of scientific rigor and integrity in all our research.
Collaborative Partnerships
and Progress
We pursue efficient pathways to bring transformative therapies to patients faster.
The Orogen Story: A New Paradigm
Forging a New Path
for Drug Development.
Orogen was founded on the conviction that there is a better, more efficient way to discover and develop small molecule therapies. We see the challenges, the long timelines, and the areas where patients are still waiting for optimal solutions. This inspired us to build a company that is both agile and scientifically powerful, capable of competing with larger entities by leveraging cutting-edge science and a deeply ingrained entrepreneurial spirit.
We thrive on a culture of responsiveness and true partnership, understanding that the journey to new medicines requires both brilliant science and unwavering dedication. Our focus is on creating oral medicines that can address diseases in a more accessible and targeted manner, starting with significant unmet needs in immuno-inflammation.
Agile Research
Our lean structure enables us to move quickly, make decisions rapidly, and pivot when the science points us in new directions.
Cutting-Edge Science
We leverage advanced technologies and approaches that larger organizations might find challenging to implement.

Patient-Focused Solutions
Our oral medicines are designed to be more accessible and convenient, addressing diseases in a targeted manner with fewer side effects.
Our Core Values: The Principles
That Guide Us
Patient-Centricity
Our work begins and ends with the patient. Their needs are the driving force behind our research and the benchmark for our success. We strive to bring hope and new possibilities to individuals and their families.
Scientific Excellence & Rigor
We are committed to the highest standards of scientific inquiry. Our innovative platform integrates advanced technologies like focused DNA-Encoded Libraries (FocusDEL™) and machine learning, but always anchored in solid experimental work and guided by expert human insight. Credibility is paramount.
Bold Innovation
We are not afraid to challenge conventional thinking and explore novel approaches to drug discovery. Our aim is to be at the forefront of molecular innovation, creating therapies that are truly different and better.
Collaborative Spirit
We believe in the power of collaboration, both within our diverse, expert team and with external partners. Great science thrives on shared knowledge and purpose.
Integrity & Purpose
We operate with unwavering integrity in all our endeavors, driven by the profound purpose of making a meaningful difference in the world through transformative medicines.
Our North Star
These core values unite and guide our team in every decision we make and every therapy we develop. They are not just aspirational statements, but the principles we embody every day as we work to transform medicine.
Our Commitment
Orogen Therapeutics is more than a biotech company; we are a dedicated team committed to the relentless pursuit of scientific breakthroughs that translate into real-world benefits for patients. We are building a future where innovative oral medicines provide new hope and improved quality of life for those facing serious diseases. Our commitment encompasses rigorous ethical standards, continuous learning, and the drive to not just discover, but to deliver.
The pioneering science that powers our mission is driven by an exceptional group of individuals.
Learn more about the innovative engine behind our discoveries.
"Orogen is elevating new heights in drug discovery, integrating massive chemical libraries, target-specific screening, and AI-based computation to propel the generation of novel medicines."
Mark Pykett
CEO, Orogen Therapeutics