Reimagining the small-molecule drug discovery paradigm

Creating better medicines through machine-assisted molecular innovation anchored in solid experimental work and guided by human insight. our mission is to rapidly and effectively deliver groundbreaking clinical solutions to patients with serious unmet medical needs.

Orogen’s proprietary platform

Pioneering a novel drug discovery approach integrating proprietary focused DNA-encoded libraries (FocusDEL™), virtual screening and bespoke chemical adaptation, powered by machine learning and a world-class team, to derive novel chemical matter for medically-important targets.

our process

Pipeline

Key targets for inflammatory, immune and other diseases enabled by DEL discovery.

Predict

Co-optimize activity, synthesis, safety and efficacy.

Provide

Efficiently derive novel drug candidates in less time at lower cost.

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who we are

A team of creative veteran scientists with decades of drug development experience and a deep, abiding interest in all aspects of small molecule R&D: data science, cutting- edge AI, DNA-encoded libraries, focused libraries, target evaluation, chemistry, biochemistry and biophysics.

or·o·gen

/ˈôrəj(ə)n/

Noun: the mountain-forming layer of earth's crust

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